Use Of Psychiatric Medications During Pregnancy And Lactation Acog Practice Bulletin Pdf

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Published: 28.05.2021

The treatment of depression during pregnancy is both a common and complex clinical challenge. The decision to expose the fetus to antidepressant medication during pregnancy must be weighed against the risks of untreated maternal depression to both mother and fetus. Maternal depression during pregnancy has been associated with increased rates of preterm birth and maternal substance use.

Flowchart of exposure groups. Arch Gen Psychiatry. Exposure was defined as prescriptions filled.

THE EFFECTS OF ANTIDEPRESSANT MEDICATIONS ON MOTHERS AND BABIES

Listed below are selected guidelines and recommendations for treating and managing various health conditions during pregnancy. This information is not comprehensive and does not include all treatments or methods. Asthma controller therapy during pregnancy Am J Obstet Gynecol. Managing asthma during pregnancy: recommendations for pharmacologic treatment—Update These NIH recommendations, updated during , provide guidance on medication treatment for pregnant women with asthma. Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy an evidence based review : Teratogenesis and perinatal outcomes Neurology. Public Health Service Task Force recommendations for use—of antiretroviral drugs in pregnant HIV-1—infected women for maternal health and interventions to reduce perinatal HIV-1 transmission in the United States [ Read recommendation s].

Antidepressant Use During Pregnancy: Current Controversies and Treatment Strategies

Read terms. ABSTRACT: It is estimated that more than , pregnancies in the United States each year involve women who have psychiatric illnesses that either predate or emerge during pregnancy, and an estimated one third of all pregnant women are exposed to a psychotropic medication at some point during pregnancy 1. The use of psychotropic medications is a cause of concern for physicians and their patients because of the potential teratogenic risk, the risk of perinatal syndromes or neonatal toxicity, and the risk for abnormal postnatal behavioral development. With the limited information available on the risks of the psychotropic medications, clinical management must incorporate an appraisal of the clinical consequences of offspring exposure, the potential effect of untreated maternal psychiatric illness, and the available alternative therapies. The purpose of this document is to present current evidence on the risks and benefits of treatment for certain psychiatric illnesses during pregnancy. ACOG Clinical is designed for easy and convenient access to the latest clinical guidance for patient care. Individual subscriptions include print and online access.

Prescription and over the counter medication use during pregnancy and lactation is exceedingly common. There are many available resources to gather information and guide patient counseling. These include primary literature, online resources, professional society recommendations, and the drug label. One must consider both disease and drug characteristics when making decisions on medication use during pregnancy and lactation. Providers can then use this information to balance the risks of fetal or neonatal exposure against the potential benefits of maternal treatment and the risks of untreated disease. The purpose of this document is to highlight our suggested best available resources and to provide a clinical approach for decisions regarding medication use during pregnancy and lactation.

Obstetric and Fetal Pharmacology and the focus on psycho pharmacology is an important clinical issue for physicians and patients because of the potential for teratogenic risk, perinatal syndromes, and effect on neonatal development. Decisions regarding treatment should be a shared decision between obstetric and mental health clinicians, and the patient before the pregnancy occurs whenever possible. Untreated psychiatric illness comes with its own risks, including significant impacts on maternal and neonatal health, including suicide and infanticide. All psychotropic medications will cross the placenta, be present in amniotic fluid, and enter breast milk. The highest risk for teratogenesis is during embryogenesis, from the 3rd to 8th week of gestation.


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Use of Psychiatric Medications During Pregnancy and Lactation

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Korin Richardson; Antipsychotic use during pregnancy and lactation: optimizing health for mother and newborn.

2 Response
  1. Amanda M.

    Pregnancy, depression, antidepressants, risk:benefit discussions, poor neonatal adaptation syndrome, persistent pulmonary hypertension of the newborn.

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